Study finds puberty blocking measures did not lead to increase in suicide

Study finds puberty blocking measures did not lead to increase in suicide

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There is no evidence of a significant increase in suicides among young patients attending a gender identity clinic in London, an independent study has found.

Professor Louis Appleby has been commissioned by Health Secretary Wes Streeting to review the data following campaigners’ claims that suicide rates have increased since puberty-blocking drugs were restricted at the Tavistock and Portman NHS Trust in 2020.

Professor Appleby’s analysis concludes that “the data do not support this claim” and he adds that the way the topic was approached on social media was “insensitive, distressing and dangerous”.

Jo Maugham, founder of the Good Law Project which led the lawsuits, said he had “deep difficulties” with the study, saying its analysis also included patients on waiting lists.

Dangerous language

The Department of Health and Social Care said it was essential that public debate around the issue was conducted responsibly.

Professor Appleby, professor of psychiatry and senior suicide researcher at the University of Manchester, said online discussions about the issue had run counter to guidelines on the safe reporting of suicides.

“One risk is that young people and their families will be terrified by predictions that suicide is inevitable without puberty blockers – some of the reactions on social media show that,” he said.

There was also the risk that distressed adolescents hearing this message would be led to copy the behavior they were being warned against.

He also said that public claims of an “explosion” in suicides “do not meet basic standards of statistical evidence.”

The Good Law Project is challenging the former health minister’s decision to end the prescribing of puberty-blocking drugs by private clinics to children and young people with gender dysphoria.

That was recommended by the Cass report, published in April, which found “remarkably weak” evidence on the use of the treatment.

In response to their allegations, the new Health Secretary launched an independent review led by Professor Appleby which analysed NHS England data on patient suicides at the Tavistock clinic, based on an audit of the facility.

Covering the period between 2018-19 and 2023-24, it found there were 12 suicides – five in the three years to 2020-21 and seven in the three years after.

“There is virtually no difference,” Professor Appleby says in his report, “given the expected fluctuations in small numbers, and it would not reach statistical significance.”

He adds: “In the under-18s specifically, there were 3 suicides before and 3 after 2020-21.”

The patients who died were at different stages of the care system, including after discharge, suggesting there was no consistent link to any aspect of care, Professor Appleby noted.

However, he said it was likely there had been an increase over a longer period as more at-risk young people came forward with gender identity issues.

‘Insufficient evidence’

The Good Law Project based its allegations on information provided by whistleblowers at the now-closed Tavistock Clinic.

The project’s executive director, Mr Maugham, said in a lengthy response to the review on X, formerly Twitter, that this had been combined with public evidence from Tavistock’s own minutes.

He said freedom of information requests for the official figures had been “rejected” and that Tavistock and NHS England had declined to comment on its findings when contacted.

Mr Maugham said on X: “We seem to be comparing apples and pears.

“The DHSC advisor refers to the small group of ‘current and former GIDS patients’, whereas my figures relate mainly to the wider group of ‘those on the waiting list’.

A spokesperson for the Department of Health and Social Care said decisions about children’s healthcare must always be based on evidence.

“Dr Cass’s review found there was insufficient evidence to show puberty blockers were safe for under-18s, which is why the NHS has already stopped routinely prescribing them to children with gender dysphoria.

“We are committed to ensuring that children who are questioning their gender receive the best possible multidisciplinary care, led by clinical experts. That is why we are reforming gender identity services.

“It is essential that the public debate around this issue is conducted with sensitivity and responsibility.”